William Holmes may refer to:

• William Holmes (academic), Vice-Chancellor of Oxford University 1732–1735
• William Holmes (1779-1851), British Tory politician of the early nineteenth century
• William Edgar Holmes, English recipient of the Victoria Cross
• William Holmes (Australian general), Australian General from World War I
• William Holmes (British general), British General of World War II
• William Holmes (cyclist), British cyclist who competed at the 1956 Summer Olympics
• William Holmes (anarchist), eminent US anarchist in the late 19th century
• William Henry Holmes (1846–1933), anthropologist

This disambiguation page lists articles associated with the same personal name. If an article link led you here, you may wish to change the link to point directly to the intended article.