WMD may refer to:

• Weapon of mass destruction, a term used to describe munitions with the capacity to kill large numbers of human beings indiscriminately
• Weighted mean difference, a measure in statistical meta-analysis
• Wetland management district, a type of conservation area
• World Movement for Democracy, an initiative to strengthen collaboration among those working to promote democratic values and institutions
• WMD, IATA code of Mandabe airport
• Westmead railway station, Sydney has station code WMD
• Wymondham railway station has National Rail code WMD
• Wipe Me Down, a rap single by Foxx
• WMD a single by Blow Up Hollywood

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