USD stands for:
- United States dollar, the official currency of the United States
- University of San Diego, San Diego, California, USA
- University of South Dakota, Vermillion, South Dakota, USA
- Under Secretary of Defense, the third-highest ranking position in the U.S. Department of Defense.
- Unified school district, an Identification Number for most public schools in America (e.g., Wichita, Kansas's school district number is 259).
- Universal Skate Design, an aggressive in-line skating company
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