• Ellen Cleghorne, Siobhan Fallon and Robert Smigel's first episode as cast members

• Ted Danson, Kelsey Grammer, Woody Harrelson and George Wendt make appearances as themselves in the opening monologue.

• John McLaughlin makes an appearance as himself in the cold opening.

• Edward Furlong appears as his Terminator 2 character John Conner in a Terminator parody.
• Martin Scorsese appears as himself in The Chris Farley Show.
• Beth Cahill and Melanie Hutsell's first episode as cast members

• Kieran Culkin appears as Froggy in a Richmeister sketch.
• George Wendt reprises his role as Bob Swerski in Bill Swerski's Super Fans.

• During the live closing credits, the members of Nirvana pretended to "make out" with each other, an event referenced in the original liner notes to their album Incesticide. As a result, NBC replaced the closing credits with those from the rehearsal taping for all subsequent re-runs.
• Rob Morrow shows a clip from the "Substitute Judge" sketch on the season five episode hosted by Rodney Dangerfield during the monologue, pointing out that Morrow played one of the jurors.

Tom Arnold

• Madonna appears in a Coffee Talk sketch as a panelist. In the end of the Coffee Talk sketch, Barbra Streisand makes an appearance as herself (Madonna, Myers and Roseanne were not told in advance that Streisand would be making an appearance, so their reaction in the sketch is their actual reaction to her surprise appearance).
• During the Red Hot Chili Peppers' performance of "Stone Cold Bush", singer Anthony Kiedis hits guitarist John Frusciante with his microphone. This upset the already unhappy Frusciante, who then proceeded to play "Under the Bridge" off key and scream nonsense during the chorus.

• Joe Pesci was originally supposed to host this episode, but had to back out due to a prior engagement. Tom Hanks spoofed Pesci's role in GoodFellas after his monologue in a sketch with Phil Hartman.

• Victoria Jackson, Beth Cahill and Siobhan Fallon's final episode as cast members.