Robert Walpole may refer to:

• Robert Walpole (1650-1700), Member of Parliament for Castle Rising, 1689–1700
• Robert Walpole, 1st Earl of Orford (1676–1745), Prime Minister of Great Britain, 1721–1742
• Robert Walpole, 2nd Earl of Orford (1701–1751)
• Robert Walpole (ambassador) (1736–1810), clerk of the Privy Council and ambassador to Portugal
• Robert Walpole, 9th Baron Walpole (1913–1989)
• Robert Walpole, 10th Baron Walpole (b. 1938)
• Robert Walpole (cricketer) (1768-1834)

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