Mastiff may refer to:

Dog breeds

• Molosser, a group of several breeds of dog also known as Mastiffs.
• American Mastiff, a breed of dog in the Molosser group.
• Bullmastiff, said to be a cross between the English Mastiff and the Bulldog.
• English Mastiff, a breed of dog in the Molosser group.
• Spanish Mastiff, an ancient breed of dog originating in Spain.
• Neapolitan Mastiff, an ancient breed of dog originating in Italy.
• Tibetan Mastiff, an ancient breed of dog originating in Tibet.
• Dogue de Bordeaux, Bordeaux Mastiff or French Mastiff is one of the most ancient French breeds.
• Pug, a miniature breed of mastiff originating in China.
• Cane Corso, a mastiff that originated in Italy.

Other

• Mastiff UAV - a battlefield UAV built by Tadiran Electronic Industries.
• Mastiff Tech ( Software Product Development Company)
• Mastiff (company) - video game company.
• The British Army designation for the Cougar AFV

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