| Edmund of Langley, 1st Duke of York |
| Children |
| Edward of Norwich, 2nd Duke of York |
| Richard of Conisburgh, Earl of Cambridge |
| Constance, Countess of Gloucester |
| Edward of Norwich, 2nd Duke of York |
| Richard of Conisburgh, Earl of Cambridge |
| Children |
| Isabel, Countess of Essex |
| Richard Plantagenet, 3rd Duke of York |
| Richard Plantagenet, 3rd Duke of York |
| Children |
| Anne, Duchess of Exeter |
| Edward IV of England |
| Edmund, Earl of Rutland |
| Elizabeth, Duchess of Suffolk |
| Margaret, Duchess of Burgundy |
| George, Duke of Clarence |
| Richard III of England |
| Edward IV of England |
| Children |
| Elizabeth, Queen Consort of England |
| Mary of York |
| Cecily Kymbe |
| Edward V of England |
| Margaret of York |
| Richard of Shrewsbury, Duke of York |
| Anne, Countess of Surrey |
| George, Duke of Bedford |
| Catherine, Countess of Devon |
| Bridget of York |
| George, Duke of Clarence |
| Children |
| Margaret, Countess of Salisbury |
| Edward, Earl of Warwick |
| Richard III of England |
| Children |
| Edward of Middleham, Prince of Wales |
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Isabel Plantagenet (1409-2 October 1484) was the only daughter of Richard of Conisburgh, 3rd Earl of Cambridge and Anne de Mortimer. She was an older sister of Richard Plantagenet, 3rd Duke of York and, like him, simultaneously a great-grandchild (through their father) and a great-great-great grandchild (through their mother) of Edward III.
On 18 February 1413 she was either betrothed or married to Sir Thomas Grey. He was a namesake son of Sir Thomas Grey and Lady Alice Neville, daughter of Ralph Neville, 1st Earl of Westmorland and Margaret Stafford.
The engagement would presumably have been negated with the execution of her father for treason in 1415. Richard had been stripped of all his titles and estates by Henry V of England and his daughter was effectively disinherited.
She is known to have married Henry Bourchier, 1st Earl of Essex at some point prior to 1426. They were parents to at least eleven children.
Her husband died on 4 April 1483. She remained a widow and died more than a year later. She was buried in Maldon, Essex.
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