Interstate 55 was built in sections across Illinois between 1960 and the late 1970s. This expressway largely replaced former Route 66 in Illinois, and some stretches directly overlap the old highway. One can find many signs posted noting the historic route. The earliest stretches were built near Chicago along the Southwest Expressway (later renamed the Stevenson Expressway), with later portions being built downstate.
| County |
Location |
Mile |
# |
Destinations |
Notes |
| St. Clair |
East St. Louis |
Poplar Street Bridge over the Mississippi River |
|
1 |
 IL 3 south / GRR south – Cahokia |
South end of IL 3/GRR overlap |
|
|
13th Street, Tudor Avenue |
|
|
|
Fourth Street – East St. Louis Business District |
Northbound exit and southbound entrance |
|
2A |
Third Street – Eads Bridge |
Southbound exit and northbound entrance |
|
2BC |
Martin Luther King Bridge – Downtown St. Louis |
Southbound exit and northbound entrance; left exit is signed as exit 2B and right exit as 2C |
|
2 |
 I-64 east / IL 3 north (St. Clair Avenue) – Louisville |
North end of I-64/IL 3 overlap |
|
3 |
Exchange Avenue |
Southbound exit and northbound entrance |
|
|
4 |
IL 203 / Collinsville Road – Fairmont City, Granite City |
Signed as exits 4A (south) and 4B (north) southbound |
| Madison |
Fairmont City |
|
6 |
 IL 111 / GRR north – Wood River, Washington Park |
North end of GRR overlap |
| Collinsville |
|
9 |
Black Lane |
Northbound exit and southbound entrance |
|
10 |
 I-255 to I-270 – Memphis |
|
|
11 |
IL 157 – Collinsville, Edwardsville |
|
| Maryville |
|
15 |
IL 159 – Collinsville, Maryville |
Signed as exits 15A (south) and 15B (north) |
|
|
17 |
US 40 east – St. Jacob, Highland |
North end of US 40 overlap |
| Troy |
|
18 |
IL 162 – Troy |
|
| North end of I-70 overlap |
|
|
20A |
I-70 east – Indianapolis |
|
|
|
20B |
I-270 west – Kansas City |
|
|
|
23 |
IL 143 – Edwardsville, Marine |
|
| Hamel |
|
30 |
IL 140 – Alton, Greenville |
|
|
|
33 |
IL 4 – Staunton, Lebanon |
|
| Livingston |
|
37 |
Livingston, New Douglas |
|
| Macoupin |
|
|
41 |
Staunton |
|
| White City |
|
44 |
IL 138 – Mount Olive, Benld |
|
| Montgomery |
Litchfield |
|
52 |
IL 16 – Gillespie, Litchfield |
|
|
|
60 |
IL 108 – Carlinville |
|
|
|
63 |
 IL 48 / IL 127 – Raymond, Taylorville, Hillsboro |
|
| Farmersville |
|
72 |
Farmersville, Girard |
|
| Sangamon |
Divernon |
|
80 |
Divernon |
|
|
|
82 |
IL 104 – Pawnee, Auburn |
|
|
|
83 |
Glenarm |
|
| Springfield |
|
88 |
East Lake Drive – Chatham |
|
|
90 |
Toronto Road |
|
|
92A |
I-55 Bus. north (6th Street) |
|
| South end of I-72/US 36 overlap |
|
92B |
 I-72 west / US 36 west – Jacksonville |
|
|
94 |
Stevenson Drive, East Lake Drive |
|
|
96 |
IL 29 (South Grand Avenue) – Taylorville |
Signed as exits 96A (south) and 96B (north) |
|
98A |
 I-72 east / US 36 east – Decatur |
|
| North end of I-72/US 36 overlap |
|
98B |
IL 97 west (Clear Lake Avenue) |
|
|
100 |
IL 54 east (Sangamon Avenue) – Clinton |
Signed as exits 100A (east) and 100B (west) |
| Sherman |
|
105 |
I-55 Bus. south – Springfield, Sherman |
|
| Williamsville |
|
109 |
Williamsville (IL 123) |
|
| Logan |
Elkhart |
|
115 |
Elkhart |
|
|
|
119 |
Broadwell |
|
|
|
123 |
I-55 Bus. north – Lincoln |
|
| Lincoln |
|
126 |
 IL 10 / IL 121 – Lincoln, Mason City |
|
|
|
127 |
I-155 north – Peoria, Hartsburg |
|
|
|
133 |
I-55 Bus. south – Lincoln, Lawndale |
|
|
|
140 |
Atlanta, Lawndale |
|
| McLean |
|
|
145 |
US 136 – McLean, Heyworth |
|
|
|
154 |
Shirley |
|
|
|
157A |
 I-74 east / US 51 south – Indianapolis, Decatur |
South end of US 51 overlap |
| South end of I-74 overlap |
| Bloomington |
|
157B |
I-55 Bus. north (Veterans Parkway) |
Signed as exit 134B southbound |
|
160 |
 US 150 / IL 9 (Market Street) – Pekin |
|
| North end of I-74 overlap |
|
|
163 |
I-74 west – Peoria |
|
|
|
164 |
 I-39 north / US 51 north – Rockford |
North end of US 51 overlap |
| Normal |
|
165 |

US 51 Bus. – Bloomington-Normal |
Signed as exits 165A (south) and 165B (north) northbound |
|
167 |
I-55 Bus. south (Veterans Parkway) – Central Illinois Regional Airport |
|
|
|
171 |
Towanda |
|
| Lexington |
|
178 |
Lexington |
|
| Chenoa |
|
187 |
US 24 – El Paso, Chenoa |
|
| Livingston |
Pontiac |
|
197 |
IL 116 – Flanagan, Pontiac |
|
|
|
201 |
IL 23 – Pontiac, Streator |
|
|
|
209 |
Odell |
|
|
|
217 |
IL 17 – Streator, Kankakee |
|
| Grundy |
|
|
220 |
IL 47 – Dwight, Morris |
|
|
|
227 |
IL 53 – Gardner |
|
|
|
233 |
Reed Road – Braidwood |
|
| Will |
|
|
236 |
IL 113 – Kankakee, Coal City |
|
|
|
238 |
IL 129 south – Braidwood |
|
|
|
240 |
Lorenzo Road |
|
|
|
241 |
Wilmington |
|
|
|
245 |
Arsenal Road |
|
|
|
247 |
Bluff Road |
|
| Channahon |
|
248 |
US 6 – Joliet, Morris |
|
|
|
250 |
I-80 – Iowa, Indiana |
Signed as exits 250A (east) and 250B (west) |
| Shorewood |
|
251 |
IL 59 – Shorewood, Plainfield |
Northbound exit and southbound entrance |
|
253 |
US 52 – Joliet, Shorewood |
|
| Joliet |
|
257 |
US 30 – Aurora, Joliet |
|
| Plainfield |
|
261 |
IL 126 west – Plainfield |
Southbound exit and northbound entrance |
| Romeoville |
|
263 |
Weber Road |
|
| Bolingbrook |
|
267 |
IL 53 – Bolingbrook, Romeoville |
|
|
268 |
Joliet Road south |
Southbound exit and northbound entrance |
|
269 |
I-355 (Veterans Memorial Tollway) – Northwest Suburbs, Southwest Suburbs |
|
| DuPage |
Darien |
|
271 |
Lemont Avenue |
Signed as exits 271A (south) and 271B (north) |
|
273 |
Cass Avenue |
Signed as exits 273A (south) and 273B (north) |
| Willowbrook |
|
274 |
IL 83 (Kingery Road) |
|
| Burr Ridge |
|
276 |
County Line Road |
Signed as exits 276A (south) and 276B (north) |
| Cook |
| Indian Head Park |
|
276C |
Joliet Road |
Northbound exit and southbound entrance |
|
277 |
I-294 (Tri-State Tollway) – Indiana, Wisconsin |
Signed as exits 277A (north) and 277B (south); southbound exit to I-294 south is via exit 279A |
| Countryside |
|
279 |
  US 12 / US 20 / US 45 (La Grange Road) |
Signed as exits 279A (east/south) and 279B (west/north) |
| Hodgkins |
| Summit |
|
282 |
IL 171 (1st Avenue) |
Signed as exits 282A (south) and 282B (north) northbound |
|
283 |
IL 43 (Harlem Avenue (7200 West)) |
|
| Chicago |
|
285 |
Central Avenue (5600 West) |
|
|
286 |
IL 50 (Cicero Avenue (4800 West)) – Chicago Midway Airport |
|
|
287 |
Pulaski Road (4000 West) |
|
|
288 |
Kedzie Avenue (3200 West) |
Southbound exit and northbound entrance |
|
289 |
California Avenue (2800 West) |
Northbound exit and southbound entrance |
|
290 |
Damen Avenue (2000 West) |
|
|
290 |
Ashland Avenue (1600 West) |
Northbound exit and southbound entrance |
|
292 |
 I-90 / I-94 (Dan Ryan Expressway) – Indiana, Wisconsin |
Signed as exits 292A (west) and 292B (east) northbound, and as exits 292 (west) and 293B (east) southbound |
|
293A |
Cermak Road – Chinatown (2200 South) |
Northbound exit and southbound entrance |
|
293C |
State Street (0 East/West) |
Southbound exit and northbound entrance |
|
293D |
Martin L. King Drive (400 East) |
Northbound exit and southbound entrance |
| 294.38 |
|
US 41 (Lake Shore Drive) |
Northbound exit and southbound entrance |