Clodius is the Roman nomen Claudius altered to a spelling that would have sounded plebeian to Roman ears. The original alteration was a political maneuver by Publius Clodius Pulcher.
- Publius Clodius Pulcher, Republican politician
- Clodia, second sister of Publius Clodius
- Clodius Aesopus, tragedian 50s BC
- Caius Clodius Vestalis, possible builder of Via Clodia
- Publius Clodius Thrasea Paetus, senator during Nero's reign
- Lucius Clodius Macer, legatus who revolted against Nero
- Publius Clodius Quirinalis, from Arelate in Gaul, teacher of rhetoric in time of Nero
- Decimus Clodius Albinus, rival emperor 196-197
- Marcus Clodius Pupienus Maximus, co-emperor 238
- Clodius Celsinus Adelphus, Prefect, the father of:
- Quintus Clodius Hermogenianus Olybrius (born ca 335), Consul in 379
Clodio the Longhair, a chieftain of the Salian Franks, is sometime called "Clodius I".
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